Thermo Fisher Scientific JMJD2C Polyclonal Antibody
Rabbit polyclonal antibody targeting human JMJD2C (KDM4C) for Western blot applications. Recognizes histone demethylase involved in H3 Lys-9 and Lys-36 demethylation. Supplied as liquid, unconjugated, 1.0 mg/mL concentration. Suitable for HeLa and U87-...
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Applications
- Western Blot (WB): Tested dilution 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human KDM4C (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2736029 |
Product Specific Information
- Positive Control: HeLa, U87-MG
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Jumonji domain-containing protein 2C (JMJD2C), also known as Lysine-specific demethylase 4C (KDM4C), is a histone demethylase that specifically demethylates Lys-9 and Lys-36 residues of histone H3, playing a central role in the histone code.
KDM4C does not demethylate histone H3 Lys-4, H3 Lys-27, or H4 Lys-20. It acts on trimethylated H3 Lys-9 and H3 Lys-36 residues, with no activity on mono- or dimethylated forms. Demethylation of Lys residues generates formaldehyde and succinate.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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