Thermo Fisher Scientific KIAA1530 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human KIAA1530. Recombinant protein control fragment (Product #RP-100208). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KIAA1530,uniProtId:Q2YD98-1,ncbiNodeId:9606,antigenRange:486-584,antigenLength:709,antigenImageFileName:PA5-62252_KIAA1530_Q2YD98-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62252_KIAA1530_Q2YD98-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643054

Product Specific Information

Immunogen sequence: PQEAQKLAAE RARAPVVPYG VDLHYWGQEL PTAGKIVKSD SQHRFWKPSE VEEEVVNADI SEMLRSRHIT FAGKFEPVQH WCRAPRPDGR LCERQDRLK

Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 81%.

Target Information

The protein encoded by KIAA1530 appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex, and is thought to be involved in the transcription-coupled nucleotide excision repair (TC-NER) pathway to help remove lesions in the DNA that block transcription. Defects in KIAA1530 can cause UV-sensitive syndrome 3. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.