Thermo Fisher Scientific KIAA1530 Polyclonal Antibody
인간 KIAA1530 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 40% 글리세롤 포함. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human KIAA1530. Recombinant protein control fragment (Product # RP-100208) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2643054 |
Product Specific Information
Immunogen sequence:
PQEAQKLAAE RARAPVVPYG VDLHYWGQEL PTAGKIVKSD SQHRFWKPSE VEEEVVNADI SEMLRSRHIT FAGKFEPVQH WCRAPRPDGR LCERQDRLK
Highest antigen sequence identity to orthologs:
- Mouse: 81%
- Rat: 81%
Target Information
The protein encoded by KIAA1530 is involved in the ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. It interacts with members of the nucleotide excision repair complex and plays a role in the transcription-coupled nucleotide excision repair (TC-NER) pathway, helping remove DNA lesions that block transcription.
Defects in KIAA1530 can cause UV-sensitive syndrome 3.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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