Thermo Fisher Scientific SCP2 Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal SCP2 항체로, WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 장기 보관 시 -20°C 권장. 지방 대사 관련 SCP2 단백질 연구용으로 적합.
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Thermo Fisher Scientific SCP2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SCP2. Recombinant protein control fragment (Product #RP-94062). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647025 |
Product Specific Information
Immunogen sequence:
GKKALADAQI PYSAVDQACV GYVFGDSTCG QRAIYHSLGM TGIPIINVNN NCATGSTALF MARQLIQGGV AECVLALGFE KMSKGSLGIK FSDRTIPTDK H
Highest antigen sequence identity to the following orthologs:
- Mouse: 85%
- Rat: 83%
Target Information
This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), resulting from transcription initiation from two independently regulated promoters.
- The proximal promoter encodes the longer SCPx protein.
- The distal promoter encodes the shorter SCP2 protein, sharing a common C-terminus.
SCPx is a peroxisome-associated thiolase involved in oxidation of branched-chain fatty acids. SCP2 functions as an intracellular lipid transfer protein. This gene is highly expressed in organs related to lipid metabolism and may be associated with Zellweger syndrome, which involves peroxisome deficiency and impaired bile acid synthesis.
Alternative splicing produces multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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