Thermo Fisher Scientific EPB42 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human EPB42. Recombinant protein control fragment (Product #RP-98173). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EPB42,uniProtId:P16452-1,ncbiNodeId:9606,antigenRange:578-683,antigenLength:691,antigenImageFileName:PA5-59127_EPB42_P16452-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59127_EPB42_P16452-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641064

Product Specific Information

Immunogen sequence: FAQEDIAICR PHLAIKMPEK AEQYQPLTAS VSLQNSLDAP MEDCVISILG RGLIHRERSY RFRSVWPENT MCAKFQFTPT HVGLQRLTVE VDCNMFQNLT NYKSVT

Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 68%.

Target Information

Erythrocyte membrane protein band 4.2 is an ATP-binding protein which may regulate the association of protein 3 with ankyrin. It probably has a role in erythrocyte shape and mechanical property regulation. Mutations in the EPB42 gene are associated with recessive spherocytic elliptocytosis and recessively transmitted hereditary hemolytic anemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.