Thermo Fisher Scientific CD304 (Neuropilin-1) Monoclonal Antibody (A3-D1)
CD304 (Neuropilin-1) 단일클론 항체(A3-D1)는 인간 및 마우스 반응성을 가지며 WB, IHC, ICC/IF에 적합합니다. Protein A로 정제된 액상 항체로 PBS 기반 저장용액에 포함되어 있으며, VEGF 및 신경계 관련 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:400 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A3-D1 |
| Immunogen | Recombinant protein with mouse Neuropilin 1 aa 856–923 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% Glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802505 |
Target Information
Neuropilin 1 is a 923 amino acid membrane-bound coreceptor belonging to the neuropilin family. It contains two CUB domains, two F5/8 type C domains, and a MAM domain. Neuropilin 1 forms heterodimers with Neuropilin 2 (NRP2) and interacts with plexin (PLXNB1) to form semaphorin receptors. Predominantly expressed in the nervous system, it plays roles in cardiovascular development, angiogenesis, axon guidance, neuronal circuit formation, cell survival, neuronal migration, and organogenesis. It functions as a receptor for semaphorins and vascular endothelial growth factor (VEGF), regulating VEGF-induced angiogenesis. Neuropilin 1 may be associated with advanced prostate carcinoma and breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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