Thermo Fisher Scientific UBE2C Monoclonal Antibody (2001CT211.37.61)
Human UBE2C 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 적합. Protein G로 정제된 액상 형태이며, PBS buffer에 sodium azide 포함. 세포주기 및 암 연구에 활용 가능. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2001CT211.37.61 |
| Immunogen | KLH conjugated synthetic peptide between 137–172 amino acids from the C-terminal region of human UBE2C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897695 |
Target Information
This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. It accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, it catalyzes Lys-11- and Lys-48-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. It initiates Lys-11-linked polyubiquitin chains on APC/C substrates, leading to their degradation by the proteasome and promoting mitotic exit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: MA5-37771_UBE2C_O00762-1_House_mouse.svg, MA5-37771_UBE2C_O00762-1_House_mouse_PDP.jpeg)
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