Thermo Fisher Scientific TCP1 Recombinant Rabbit Monoclonal Antibody (JE48-48)
TCP1 단백질을 표적하는 재조합 토끼 단클론 항체로, WB 및 IHC에 적합합니다. HEK293 발현 시스템 기반으로 생산되며 Protein A로 정제되었습니다. 고순도 액상 형태로 안정적인 신호 검출에 최적화되어 있습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE48-48 |
| Immunogen | Recombinant protein within Human TCP1 alpha aa 1–97 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2848769 |
Product Specific Information
Positive Control: Daudi, human liver cancer tissue, human skin tissue, human breast tissue.
Target Information
The T Complex Polypeptide 1 (TCP-1) is an approximately 60 kDa protein constitutively expressed in almost all eukaryotic cells and upregulated during spermatogenesis. It is found in the cytosol as a subunit of a hetero-oligomeric chaperone involved in the folding of actin and tubulin.
Chaperonins recognize and stabilize polypeptide intermediates during folding, assembly, and disassembly, sharing characteristics with Heat Shock Protein 70 (HSP70) such as high abundance, induction by environmental stress, and ATPase activity.
The chaperonin family includes mitochondrial HSP60, E. coli GroEL, the plastid Rubisco-subunit binding protein, and the archaebacterial protein TF55. The TCP-1 sequence shows nearly 40% identity to TF55 but only minimal similarity to HSP60 and GroEL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(해당 항체의 항원 관련 이미지: MA5-34861_TCP1_P17987-1_Rabbit.svg 및 MA5-34861_TCP1_P17987-1_Rabbit_PDP.jpeg)
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