
Thermo Fisher Scientific ASL Monoclonal Antibody (OTI3D4), TrueMAB
ASL 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot 및 IHC(Paraffin) 분석에 적합합니다. 인간 ASL 전장 재조합 단백질로 면역화되었으며, 동결건조 형태로 제공되어 안정적 보관이 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D4 |
| Immunogen | Full length human recombinant protein of human ASL produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ASL encodes a member of the lyase 1 family. The protein forms a cytosolic homotetramer and catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, a key step in ammonia detoxification via the urea cycle.
Mutations cause argininosuccinic aciduria (argininosuccinic acid lyase deficiency). A pseudogene is located on chromosome 22, and alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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