Thermo Fisher Scientific CAMSAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-650 of human CAMSAP1 (NP_0562623) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CAMSAP1,uniProtId:Q5T5Y3-1,ncbiNodeId:9606,antigenRange:350-650,antigenLength:1602,antigenImageFileName:PA5-116776_CAMSAP1_Q5T5Y3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-116776_CAMSAP1_Q5T5Y3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.83 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2901407

Product Specific Information

Positive Samples: HeLa

Immunogen sequence: KTVLHQKSSR PPVPISNATK RSFLGSPAAG TLAELQPPVQ LPAEGCHRHY LHPEEPEYLG KGTAAFSPSH PLLPLRQKQQ KSIQGEDIPD QRHRSNSLTR VDGQPRGAAI AWPEKKTRPA SQPTPFALHH AASCEVDPSS GDSISLARSI SKDSLASNIV NLTPQNQPHP TATKSHGKSL LSNVSIEDEE EELVAIVRAD VVPQQADPEF PRASPRALGL TANARSPQGQ LDTSESKPDS FFLEPLMPAV LKPAKEKQVI TKEDERGEGR PRSIVSRRPS EGPQPLVRRK MTGSRDLNRT F

Target Information

Key microtubule-organizing protein that specifically binds the minus-end of non-centrosomal microtubules and regulates their dynamics and organization (PubMed:19508979, PubMed:21834987, PubMed:24486153, PubMed:24706919, PubMed:24117850). Specifically recognizes growing microtubule minus-ends and stabilizes microtubules (PubMed:24486153, PubMed:24706919). Acts on free microtubule minus-ends that are not capped by microtubule-nucleating proteins or other factors and protects microtubule minus-ends from depolymerization (PubMed:24486153, PubMed:24706919). In contrast to CAMSAP2 and CAMSAP3, tracks along the growing tips of minus-end microtubules without significantly affecting the polymerization rate: binds at the very tip of the microtubules minus-end and acts as a minus-end tracking protein (-TIP) that dissociates from microtubules after allowing tubulin incorporation (PubMed:24486153, PubMed:24706919). Through interaction with spectrin may regulate neurite outgrowth (PubMed:24117850). [UniProt]

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.