Thermo Fisher Scientific H3K18ac Recombinant Rabbit Monoclonal Antibody (23GB4465)
Histone H3K18ac에 특이적인 recombinant rabbit monoclonal antibody로, Western blot 및 Flow cytometry에 적합합니다. Human과 Mouse 시료에 반응하며, HEK293F 시스템에서 발현되었습니다. 액상 형태로 -20°C에 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB4465 |
| Immunogen | A synthesized peptide derived from Histone H3 (acetyl K18) (11–25AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3, along with four core histone proteins, binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability.
Post-translationally, histones are modified in various ways to either directly change the chromatin structure or enable the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the nucleosome core and can undergo several types of post-translational modifications, such as methylation, acetylation, and phosphorylation, which influence cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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