Thermo Fisher Scientific SYVN1 Polyclonal Antibody
SYVN1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Human, Mouse, Rat에 반응합니다. WB, IHC, ICC, Flow, ELISA 등 다양한 응용에 적합합니다. Protein A 정제, 1 mg/mL 농도의 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SYVN1 (amino acids 531–617) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HRD1 is a ubiquitin ligase induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. It protects cells from apoptosis by degrading abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, with strong expression in brain, pancreas, liver, kidney, and skeletal muscle. Synoviolin/Hrd1, expressed in rheumatoid synovium, is reported as a novel causative factor for arthropathy through its anti-apoptotic effects. HRD1 contains one ring-type zinc finger domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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