Thermo Fisher Scientific Human ApoE2 Recombinant Protein, PeproTech
Recombinant Human ApoE2 단백질로 지질 대사 연구에 활용 가능. E. coli 발현 시스템에서 생산된 34.3 kDa 단백질. ≥90% 순도, endotoxin <1 EU/µg. 동결건조 형태로 -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- 350-12-xxx (3개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human ApoE2 Recombinant Protein, PeproTech
Applications
Flow Cytometry (Flow)
- Tested Dilution: -
- View 1 publication
ELISA
- Tested Dilution: -
- View 1 publication
Functional Assay
- Assay-dependent
- View publication
In vitro Assay
- Tested Dilution: -
- View 4 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Human, Mouse |
| Expression System | E. coli |
| Amino Acid Sequence | MKVEQAVETE PEPELRQQTE WQSGQRWELA LGRFWDYLRW VQTLSEQVQE ELLSSQVTQE LRALMDETMK ELKAYKSELE EQLTPVAEET RARLSKELQA AQARLGADME DVCGRLVQYR GEVQAMLGQS TEELRVRLAS HLRKLRKRLL RDADDLQKCL AVYQAGAREG AERGLSAIRE RLGPLVEQGR VRAATVGSLA GQPLQERAQA WGERLRARME EMGSRTRDRL DEVKEQVAEV RAKLEEQAQQ IRLQAEAFQA RLKSWFEPLV EDMQRQWAGL VEKVQAAVGT SAAPVPSDNH |
| Molecular Weight | 34.3 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 90% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
Recombinant Human ApoE2 is a 34.3 kDa protein containing 300 amino acid residues.
This product is shipped at ambient temperature. For storage, handling, and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
ApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. These proteins facilitate lipid solubilization, maintain lipoprotein structural integrity, serve as ligands for lipoprotein receptors, and regulate enzymes involved in lipid metabolism.
ApoE is produced mainly in the liver and brain and is a constituent of all plasma lipoproteins. Its interaction with ApoE receptors enables uptake of chylomicron remnants by liver cells, essential for normal lipid metabolism. ApoE also binds with the LDL receptor (apo B/E).
Defects in ApoE cause hyperlipoproteinemia type III. ApoE exists in three major isoforms—E2, E3, and E4—differing by a single amino acid substitution. Compared with E3 and E4, E2 has the lowest receptor binding affinity. E2 allele carriers show lower total cholesterol, LDL cholesterol, and non-HDL cholesterol, with increased ApoE levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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