Thermo Fisher Scientific TYK2 Monoclonal Antibody (5A4)
TYK2 단백질을 표적으로 하는 Mouse IgG2a 단일클론 항체. Western blot, IHC, ICC/IF, ELISA에 적합. 인간 시료 반응성 확인됨. 항바이러스 면역 및 IFN 신호전달 연구에 유용. 연구용으로만 사용.
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Thermo Fisher Scientific TYK2 Monoclonal Antibody (5A4)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5A4 |
| Immunogen | TYK2 (AAH14243, 276–375 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PVCHLRLLAQ AEGEPCYIRD SGVAPTDPGP ESAAGPPTHE VLVTGTGGIQ WWPVEEEVNK EEGSSGSSGR NPQASLFGKK AKAHKAFGQP ADRPREPLWA
Target Information
Tyrosine Kinase 2 (TYK2), a member of the JAK kinase family, plays both structural and catalytic roles in type I interferon (IFN) signaling. It may contribute to anti-viral immunity. Mutations in this gene are associated with hyperimmunoglobulin E syndrome (HIES), a primary immunodeficiency characterized by elevated serum immunoglobulin E.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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