Thermo Fisher Scientific COX7B2 Polyclonal Antibody
COX7B2 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF에 적합하며 인간 및 마우스 시료에 반응. 고순도 친화 크로마토그래피 정제, 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human COX7B2 (Accession Q8TF08), corresponding to amino acid residues P4–W54 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852747 |
Product Specific Information
Antibody detects endogenous levels of total Cytochrome c Oxidase 7B2.
Target Information
The cytochrome c oxidase (COX) family of proteins functions as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP.
The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some mitochondrial and some nuclear.
COX7b and COX7b2 are 80 and 81 amino acid proteins, respectively, which exist as components of the COX complex and play an important role in electron transport.
A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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