Thermo Fisher Scientific IDH3A Polyclonal Antibody
Thermo Fisher Scientific의 IDH3A Polyclonal Antibody는 인간 IDH3A 단백질을 인식하는 토끼 IgG 항체로, Western blot과 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 안정적인 액상 형태로 연구용으로 제공됩니다.
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Thermo Fisher Scientific IDH3A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human IDH3A (Recombinant protein control fragment: Product #RP-105249) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2662921 |
Product Specific Information
Immunogen sequence:
NKMGLKGPLKT PIAAGHPSMN LLLRKTFDLY ANVRPCVSIE GYKTPYTDVN IVTI
Ortholog Sequence Identity:
- Mouse: 100%
- Rat: 100%
Target Information
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+) as electron acceptors.
Among five known isocitrate dehydrogenases, three NAD(+)-dependent enzymes are localized in the mitochondrial matrix, while two NADP(+)-dependent enzymes are mitochondrial and cytosolic.
NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer composed of two alpha subunits, one beta subunit, and one gamma subunit.
The protein described here is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-66546_IDH3A_P50213-1_Rabbit.svg)
(이미지: PA5-66546_IDH3A_P50213-1_Rabbit_PDP.jpeg)
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