Thermo Fisher Scientific PCDHGC4 Polyclonal Antibody
Thermo Fisher Scientific의 PCDHGC4 폴리클로날 항체는 인간 PCDHGC4 단백질을 인식하며, WB 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었고, 1 mg/mL 농도의 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–208 of Human PCDHGC4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548856 |
Product Specific Information
- Recommended positive controls: 293T, Raji
- Predicted reactivity: Mouse (99%), Chimpanzee (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene belongs to the protocadherin gamma gene cluster, one of three related clusters on chromosome 5. These clusters have an immunoglobulin-like organization, suggesting a unique regulatory mechanism.
The gamma gene cluster includes 22 genes divided into three subfamilies:
- Subfamily A: 12 genes
- Subfamily B: 7 genes and 2 pseudogenes
- Subfamily C: 3 genes
Each variable region exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while the constant region encodes the common cytoplasmic region.
These neural cadherin-like cell adhesion proteins likely play a role in the formation and function of specific cell-cell connections in the brain. Alternative splicing has been observed in the gamma cluster genes.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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