Thermo Fisher Scientific Naxitamab Humanized Recombinant Human Monoclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG1, kappa

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Immunogen

Human Ganglioside GD2

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

3.45 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911374

Product Specific Information

Endotoxin level < 0.01EU/µg by LAL method

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.

Target Information

Naxitamab is a humanized monoclonal antibody targeting the GD2 antigen. GD2 antigen is expressed on the surface of tumors generated by neuroectoderm, including neuroblastoma, melanoma and osteosarcoma. By binding to the GD2 antigen on the tumor surface, naxitamab can trigger antibody-mediated cytotoxicity and activate the complement system in the immune system to achieve the effect of killing tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.