Thermo Fisher Scientific NTAL Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LAT2. Recombinant protein control fragment (Product #RP-102142). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NTAL,uniProtId:Q9GZY6-1,ncbiNodeId:9606,antigenRange:33-175,antigenLength:243,antigenImageFileName:PA5-82095_NTAL_Q9GZY6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-82095_NTAL_Q9GZY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2789256

Product Specific Information

Immunogen sequence: AKRSEKIYQQ RSLREDQQSF TGSRTYSLVG QAWPGPLADM APTRKDKLLQ FYPSLEDPAS SRYQNFSKGS RHGSEEAYID PIAMEYYNWG RFSKPPEDDD ANSYENVLIC KQKTTETGAQ QEGIGGLCRG DLSLSLALKT GPT

Target Information

NTAL (Non-T cell Activation Linker), also known as LAB (Linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.