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Thermo Fisher Scientific LRP6 Polyclonal Antibody
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Thermo Fisher Scientific LRP6 Polyclonal Antibody

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Rabbit polyclonal antibody targeting human LRP6 for Wnt/β-catenin signaling research. Unconjugated, liquid form, 0.2 mg/mL concentration. Suitable for various immunoassays. For research use only.

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pk
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마지막 업데이트 2025. 07. 03. 오후 07:12
Thermo Fisher Scientific PA583114 LRP6 Polyclonal Antibody 100 ul pk판매 단위 pk ·
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Thermo Fisher Scientific · Thermo Fisher Scientific LRP6 Polyclonal Antibody

Thermo Fisher Scientific LRP6 Polyclonal Antibody

제품 사양

항목 내용
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human LRP6
Conjugate Unconjugated
Form Liquid
Concentration 0.2 mg/mL
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping Conditions Wet ice
RRID AB_2790270

Product Specific Information

Immunogen sequence:
GALRCNGDAN CQDKSDEKNC EVLCLIDQFR CANGQCIGKH KKCDHNVDCS DKSDELDCYP TEEPAPQ

Target Information

LRP6 is essential for the Wnt/β-catenin signaling pathway, probably by acting as a coreceptor together with Frizzled for Wnt. It is a specific, high-affinity receptor for DKK1 and DKK2, but not DKK3. The interaction with DKK1 blocks LRP6-mediated Wnt/β-catenin signaling via LRP6 removal through Kremen proteins-mediated endocytosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(해당 제품 관련 이미지: PA5-83114_LRP6_O75581-1_Rabbit.svg, PA5-83114_LRP6_O75581-1_Rabbit_PDP.jpeg)

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