Thermo Fisher Scientific KLHL29 Polyclonal Antibody
KLHL29 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료 반응성, ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, PBS/glycerol 버퍼 저장. 연구용으로만 사용.
- 카탈로그번호
- PA5144759
- 판매단위
- pk
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 773–848). Recombinant protein control fragment: Product #RP-109856 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_3091814 |
Product Specific Information
- Immunogen sequence:
AVTLNGFVFI LGGAYARATT IYDPEKGNIK AGPNMNHSRQ FCSAVVLDGK IYATGGIVSS EGPALGNMEA YEPTTN - Antigen sequence identity: Mouse 100%; Rat 100%
Target Information
KLHL29 (Kelch-like protein 29), also known as KBTBD9, is a 655 amino acid protein related to the Drosophila Kelch protein. Mutations affecting Kelch function result in failure of Kelch to associate with ring canals, leading to female sterility.
Human KLHL29 contains six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack, and Bric a brac) domain, also known as the POZ domain, is an N-terminal homodimerization domain containing multiple kelch repeats and/or C2H2-type zinc fingers.
Proteins with BTB domains are involved in transcriptional regulation through chromatin structure control. KLHL29 exists as two alternatively spliced isoforms encoded by a gene on human chromosome 2p24.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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