Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Rat에서 반응하는 Fibulin 1 폴리클로날 항체로 Western blot에 적합합니다. Rabbit IgG로 제작되어 높은 특이성과 안정성을 제공합니다. 합성 펩타이드 면역원 기반으로 생산되었으며, 액상 형태로 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific Fibulin 1 Polyclonal Antibody
Applications
- Western Blot (WB): Tested dilution 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of rat Fibulin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691368 |
Product Specific Information
This target displays homology in the following species:
Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 77%
Target Information
Fibulin-1 is a modular glycoprotein component of the elastic extracellular matrix fibers, basement membranes, and blood. It self-associates and binds to calcium, fibronectin, laminin, nidogen, and fibrinogen. These interactions may explain its association with basement membranes, connective tissue, elastic fibers, and fibrin clots.
Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis and an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. Other studies indicate inhibition of cancer cell motility with increased Fibulin-1 exposure. The exact cellular function of Fibulin-1 remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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