Thermo Fisher Scientific SERINC3 Polyclonal Antibody
SERINC3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도. 세포막 단백질 연구 및 종양 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human SERINC3, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
TDE1, also known as tumor differentially expressed protein 1 or serine incorporator 3, is a multi-pass membrane protein located on the membranes of the Golgi apparatus within cells. It is highly expressed in neuronal populations and also found in thymus, kidney, liver, and testis. Expression levels of TDE1 in tumors can reach up to tenfold higher than in normal tissues, suggesting its involvement in cellular transformation and oncogenesis. TDE1 is believed to protect cells from serum starvation and etoposide-induced apoptosis, although the precise mechanism remains unclear and may involve aberrant methylation of TDE1 complexes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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