Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI4D9), TrueMAB
인간 CD4 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot에 적합합니다. HEK293T 세포에서 발현된 full-length CD4 단백질을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. -20°C에서 보관하며, 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4D9 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression is observed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 plays a critical role in T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also contribute to neuronal damage in immune-mediated diseases of the CNS. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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