Thermo Fisher Scientific GMFB Polyclonal Antibody
Thermo Fisher Scientific의 GMFB Polyclonal Antibody는 인간, 마우스, 랫트 시료에서 반응하며 Western blot, ICC/IF, ELISA에 적합합니다. Rabbit polyclonal IgG로 제작되었으며, 신경계 연구 및 BDNF 관련 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–140 of human GMFB (NP_004115.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.39 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914787 |
Product Specific Information
Positive test controls include: LO2, U-87MG, MCF7, Mouse brain, Mouse kidney, Mouse liver, Rat kidney.
Immunogen sequence:
MSESLVVCDV AEDLVEKLRK FRFRKETNNA AIIMKIDKDK RLVVLDEELE GISPDELKDE LPERQPRFIV YSYKYQHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNK LVQTAELTKV FEIRNTEDLT EEWLREKLGF
Target Information
This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration, and inhibits tumor cell proliferation. Overexpression of GMF in astrocytes enhances brain-derived neurotrophic factor (BDNF) production. GMF expression is increased by exercise and plays a crucial role in exercise-induced BDNF production, contributing to neuroprotection. In thymoma, GMF produced by tumor cells helps maintain T-cell development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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