Thermo Fisher Scientific Alpha SNAP Recombinant Rabbit Monoclonal Antibody (JE54-66)
Recombinant rabbit monoclonal antibody targeting human Alpha SNAP. Validated for WB and ICC/IF applications. High specificity and reproducibility with Protein A purification. Suitable for research use in human and mouse samples. Supplied in liquid form...
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Applications
- Western Blot (WB): 1:500–1:1,000
- Immunocytochemistry (ICC/IF): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JE54-66 |
| Immunogen | Recombinant protein within Human Alpha SNAP (aa 161–295) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 0.05% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890375 |
Target Information
SNAPs (soluble NSF attachment proteins), acting in concert with SNAREs (SNAP receptors) and the N-ethylmaleimide-sensitive fusion protein (NSF), are required for the fusion of transport vesicles to their target membranes in synaptic transmission, intra-Golgi transport, endosome-to-endosome fusion, and transcytotic vesicle-to-plasma membrane transport. Vesicle-to-target membrane docking occurs when the vesicle SNARE binds to its cognate target membrane SNARE. α-SNAP (or β-SNAP in brain) then binds to this docking complex and mediates the binding of NSF, forming a 20S fusion particle. ATP hydrolysis by NSF initiates the fusion process.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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