Thermo Fisher Scientific SPG7 Monoclonal Antibody (OTI1E5), TrueMAB
인간 SPG7 단백질(aa 300-573)에 특이적인 마우스 단클론 항체. Western blot 및 Immunocytochemistry에 적합. 무보존제, 동결건조 형태로 제공되며 PBS/trehalose 버퍼에 용해 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 300–573 of human SPG7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
This gene encodes a mitochondrial metalloprotease protein belonging to the AAA family. Members of this family share an ATPase domain and participate in cellular processes such as:
- Membrane trafficking
- Intracellular motility
- Organelle biogenesis
- Protein folding and proteolysis
Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: CF504417_SPG7_Q9UQ90-1_House_mouse.svg, CF504417_SPG7_Q9UQ90-1_House_mouse_PDP.jpeg)
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