Thermo Fisher Scientific K-cadherin Recombinant Rabbit Monoclonal Antibody (ARC1093)
K-cadherin 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 친화 크로마토그래피로 정제되었습니다. 안정한 액상 형태로 -20°C 보관이 권장됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1093 |
| Immunogen | Synthetic peptide corresponding to amino acids 691–790 of human K-Cadherin (CDH6, UniProt ID: P55285) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849456 |
Product Specific Information
Immunogen sequence:
DIVPEALFLP RRTPTARDNT DVRDFINQRL KENDTDPTAP PYDSLATYAY EGTGSVADSL SSLESVTTDA DQDYDYLSDW GPRFKKLADM YGGVDSDKDS
Target Information
Cadherins are transmembrane glycoproteins involved in calcium-dependent cell-cell adhesion. They play essential roles in tissue integrity and morphogenesis.
Cadherins are classified into two subgroups:
- Type I: E-cadherin (cadherin-1), N-cadherin (cadherin-2), P-cadherin (cadherin-3), R-cadherin (cadherin-4)
- Type II: K-cadherin (cadherin-6), OB-cadherin (cadherin-11)
K-cadherin (Cadherin-6) is expressed in the proximal tubule epithelium of the kidney, from which most renal cell carcinomas originate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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