Thermo Fisher Scientific RSV Fusion Protein Polyclonal Antibody

Applications

• Western Blot (WB): Tested dilution 1:100–1:2,000

Product Specifications

Product Specific Information

This antibody is reactive against Human Respiratory Syncytial Virus (RSV) and Bovine Respiratory Syncytial Virus (BRSV).

Target Information

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps. Its genome consists of single-stranded, negative-sense RNA encoding three envelope glycoproteins: a small hydrophobic (SH) protein of unknown function, a major glycoprotein (G) known as the attachment protein, and a fusion (F) protein.
The 63 kDa RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, enabling viral penetration and inducing syncytia formation (multinucleated giant cells). The F protein mediates membrane fusion between infected and neighboring cells, giving the virus its name.
While RSV typically causes mild symptoms in adults, it is a leading cause of lower respiratory tract infections and hospitalizations during infancy and childhood.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.