Thermo Fisher Scientific MYBBP1A Polyclonal Antibody
MYBBP1A 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 인간 시료에 반응하며 IHC 및 IHC(Paraffin) 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific MYBBP1A Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of human MYB binding protein (P160) 1a |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Gorilla and Chimpanzee
Target Information
The Myb family of transcription factors, including A-, B-, and c-Myb, regulate differentiation, cellular growth, and gene expression.
c-Myb is essential for hematopoietic cell proliferation and differentiation.
Myb-binding protein 1A (MYBBP1A) is a nuclear protein localized mainly in nucleoli, initially identified as a c-Myb-interacting protein.
MYBBP1A interacts with various transcription factors such as the aromatic hydrocarbon receptor (AhR), enhancing AhR-dependent gene expression.
It acts as a negative regulator of PPAR gamma coactivator 1 alpha (PGC-1α) via p38 MAPK and functions as a nucleocytoplasmic shuttling protein utilizing CRM1-dependent and independent export pathways.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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