Thermo Fisher Scientific RNF220 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human RNF220. Recombinant protein control fragment (Product #RP-94522). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:RNF220,uniProtId:Q5VTB9-1,ncbiNodeId:9606,antigenRange:44-145,antigenLength:566,antigenImageFileName:PA5-55660_RNF220_Q5VTB9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55660_RNF220_Q5VTB9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646666

Product Specific Information

Immunogen sequence: QPRPFGVPVS VDKDVHIPFT NGSYTFASMY HRQGGVPGTF ANRDFPPSLL HLHPQFAPPN LDCTPISMLN HSGVGAFRPF ASTEDRESYQ SAFTPAKRLK NC

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 27%.

Target Information

E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of SIN3B. Independently of its E3 ligase activity, acts as a CTNNB1 stabilizer through USP7-mediated deubiquitination of CTNNB1 promoting Wnt signaling (PubMed:25266658).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.