Thermo Fisher Scientific GFRA1 Monoclonal Antibody (1F5)
GFRA1 단백질을 인식하는 Mouse IgM 단일클론 항체로, Western Blot과 ELISA에 적합합니다. 인간 시료 반응성이 있으며 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능하며 -20°C에서 보관합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GFRA1 Monoclonal Antibody (1F5)
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F5 |
| Immunogen | GFRA1 (NP_005255.1, 267–360 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
CQPESRSVSS CLKENYADCL LAYSGLIGTV MTPNYIDSSS LSVAPWCDCS NSGNDLEECL KFLNFFKDNT CLKNAIQAFG NGSDVTVWQP AFPV
Target Information
Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nervous system.
Physiological responses to GDNF require the presence of glycosylphosphatidylinositol-linked protein GDNFRα, a cell surface receptor for GDNF.
The cDNAs encoding GDNFRα from human, rat, chicken, and mouse have been cloned. GDNFRα is also known as Ret ligand 1 (RETL1) or TGF-β-related neurotrophic factor receptor 1 (TrnR1), and is now termed GFR-α1.
GFR-α1 binds GDNF specifically and mediates activation of the Ret protein tyrosine kinase (PTK).
Thus, GDNF, GFR-α, and Ret PTK form a complex to transduce GDNF signaling and mediate its function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.