Thermo Fisher Scientific ESRP1 Polyclonal Antibody
인간 ESRP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB 및 IHC(P) 실험에 적합하며, 고농도(2 mg/mL) 액상 형태로 제공. PBS buffer 및 sodium azide 포함, 장기 보관 시 -20°C 권장. 마우스 및 랫트 반응 예측.
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Thermo Fisher Scientific ESRP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 6 publications |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 182–211 amino acids of human ESRP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543333 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
RBM35A, also known as ESRP1, is an mRNA splicing factor that, together with its related protein RBM35B (ESRP2), coordinates an epithelial cell-type-specific splicing program.
RBM35A contains three putative RNA recognition motifs and binds specific sequences in mRNAs. It regulates posttranscriptional expression of genes such as FGFR2, CD44, CTNND1, and ENAH, affecting protein translation via 5′ UTRs.
Recent studies suggest RBM35A may also act as a novel tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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