Thermo Fisher Scientific CYP11B2 Polyclonal Antibody

Thermo Fisher Scientific CYP11B2 Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested Dilution: 1:100

Product Specifications

Product Specific Information

• Peptide sequence: RRLAEAEMLL LLHHVLKHFL VETLTQEDIK MVYSFILRPG TSPLLTFRAI
• Sequence homology:
  • Horse: 79%
  • Human: 100%

Target Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.