Thermo Fisher Scientific PSMB10 Recombinant Rabbit Monoclonal Antibody (23GB2170)
PSMB10 단백질을 인식하는 재조합 토끼 단클론 항체로 Western blot, ICC/IF, Flow cytometry에 적합합니다. 인간, 생쥐, 랫트에서 반응하며, HEK293F 발현 시스템에서 생산되었습니다. 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB2170 |
| Immunogen | A synthesized peptide derived from human PSMB10 (215–250 AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
The 20S proteasome is a protease complex responsible for cytosolic protein degradation and generation of peptide ligands for MHC class I molecules. Upon IFN-gamma stimulation, subunits LMP2, LMP7, and MECL-1 (LMP10) replace constitutive subunits to form immunoproteasomes. These complexes enhance antigen processing and presentation efficiency. Different combinations of these subunits can result in up to 36 proteasome subsets with distinct cleavage specificities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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