Thermo Fisher Scientific STAB2 Monoclonal Antibody (OTI2E12), TrueMAB
인간 STAB2 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 인간 반응성, 비결합형 형태이며, 동결건조 상태로 제공됩니다. 연구용으로만 사용되며, 항체 재결합 및 결합 실험에 활용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1914–2194 of human STAB2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The STAB2 gene encodes a large transmembrane receptor protein involved in angiogenesis, lymphocyte homing, cell adhesion, and receptor scavenging.
This receptor includes:
- 7 fasciclin domains
- 15 EGF-like domains
- 2 laminin-type EGF-like domains
- A C-type lectin-like hyaluronan-binding Link module
It is primarily expressed on sinusoidal endothelial cells of the liver, spleen, and lymph nodes.
STAB2 binds and endocytoses ligands such as hyaluronan, LDL, bacteria, and advanced glycosylation end products, supporting its role as a scavenger receptor cycling between the plasma membrane and lysosomes.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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