Thermo Fisher Scientific FOXJ1 Polyclonal Antibody
Thermo Fisher Scientific의 FOXJ1 Polyclonal Antibody는 마우스 FOXJ1 단백질을 인식하는 토끼 다클론 항체입니다. Western blot에 적합하며, 액상 형태로 제공됩니다. FOXJ1 관련 자가면역 및 섬모 형성 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of mouse FOXJ1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688742 |
Product Specific Information
This target displays homology in the following species:
Cow: 86%; Dog: 79%; Guinea Pig: 86%; Horse: 86%; Human: 86%; Mouse: 100%; Rabbit: 83%; Rat: 100%
Target Information
Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and spontaneous autoimmunity through the repression of NF-κB activity. It also inhibits the humoral immune response in B cells. FOXJ1 deficiency leads to spontaneous and accentuated germinal center formation, implicating its role in autoimmune and inflammatory diseases. Additionally, FOXJ1 is required for cilia formation and left-right axis determination by increasing calpastatin expression, necessary for basal body anchoring to the apical cytoskeleton. FOXJ1 expression may serve as an early marker of epithelial cell differentiation, recovery, and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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