Thermo Fisher Scientific PSMA6 Polyclonal Antibody
Rabbit polyclonal antibody targeting human PSMA6 for WB, IHC, and IP applications. High specificity to proteasome alpha subunit 6. Recommended dilution 1:1,000–1:10,000. Liquid form, 1 mg/mL, stored at 4°C. Predicted cross-reactivity with rat and bovine.
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Thermo Fisher Scientific PSMA6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 196 and 246 of Human Proteasome Subunit Alpha Type 6 (PSMA6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
- Predicted to react with Rat and Bovine (based on 100% sequence identity)
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure, composed of four rings with 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits). Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome processes class I MHC peptides.
This gene encodes a member of the peptidase T1A family and a 20S core alpha subunit. A pseudogene has been identified on the Y chromosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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