Thermo Fisher Scientific NOTCH3 Polyclonal Antibody
Human NOTCH3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. HeLa 세포에서 양성 대조로 사용 가능하며, Mouse와 Rat에서도 예측 반응성이 있습니다. Protein A로 정제된 액상 형태로, 4°C 단기 또는 -20°C 장기 보관이 가능합니다.
- 카탈로그번호
- PA528082
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NOTCH3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 2256–2321 of Human Notch 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 5.26 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545558 |
Product Specific Information
- Recommended positive controls: HeLa
- Predicted reactivity: Mouse (100%), Rat (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NOTCH3 is the third discovered human homologue of the Drosophila melanogaster type I membrane protein notch. In Drosophila, notch interaction (with its cell-bound ligands delta and serrate) establishes an intercellular signaling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in humans.
NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(원본 이미지 파일명: PA5-28082_NOTCH3_Q9UM47-1_Rabbit.svg, PA5-28082_NOTCH3_Q9UM47-1_Rabbit_PDP.jpeg)
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