Thermo Fisher Scientific RBFOX1 Monoclonal Antibody (OTI1F2), TrueMAB
Human RBFOX1 단백질(aa 1-210)에 특이적인 Mouse IgG1 단클론 항체로, Western blot에 최적화되어 있습니다. 고순도(affinity chromatography)로 정제된 액상 형태이며, 연구용 RNA 결합 단백질 분석에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution
- 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–210 of human RBFOX1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Ataxin-2 binding protein 1 has an RNP motif highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene, which causes familial neurodegenerative diseases. Both ataxin-2 binding protein 1 and ataxin-2 are localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene; additional variants exist but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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