
Thermo Fisher Scientific Aquaporin 5 Polyclonal Antibody
Aquaporin 5 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot 및 IHC에 사용 가능. 사람, 생쥐, 랫트 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 동결건조 형태로 제공되며 재구성 후 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (IHC) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | (C)DHREERKKTIELTAH corresponding to amino acid residues 251–265 of rat AQP5, intracellular C-terminus |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on sample size.
- The antibody ships as a lyophilized powder at room temperature.
- Upon arrival, store at -20°C.
- Reconstituted solution can be stored at 4°C for up to 1 week.
- For long-term storage, aliquot and store at -20°C.
- Avoid multiple freeze/thaw cycles.
- Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
Aquaporins (AQP0–AQP10) are membrane water channels widely distributed in mammalian tissues.
While most AQPs transport only water, AQP3, AQP7, AQP9, and one AQP10 isoform can also transport urea and glycerol.
AQP2 is vasopressin-regulated and crucial for water reabsorption in the kidney collecting duct.
Aquaporins contribute to renal water absorption, pulmonary secretion, tear production, and cerebrospinal fluid regulation.
In the lung, AQP5 mediates water transport across the apical membrane of type I alveolar epithelial cells.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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