Thermo Fisher Scientific ACN9 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ACN9. Recombinant protein control fragment (Product #RP-92844). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SDHAF3,uniProtId:Q9NRP4-1,ncbiNodeId:9606,antigenRange:60-123,antigenLength:125,antigenImageFileName:PA5-54227_SDHAF3_Q9NRP4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54227_SDHAF3_Q9NRP4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637599

Product Specific Information

Immunogen sequence: YATALLQQAN ENRQNSTGKA CFGTFLPEEK LNDFRDEQIG QLQELMQEAT KPNRQFSISE SMKP

Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.

Target Information

Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.