Thermo Fisher Scientific JLP Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000
• Publications: [참조 없음]

Immunocytochemistry (ICC/IF)

• Tested Dilution: 1:100–1:500
• Publications: [참조 없음]

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total JIP4.

Target Information

This gene encodes an adhesion protein involved in the organization of adherens and tight junctions in epithelial and endothelial cells.
It is a calcium(2+)-independent cell-cell adhesion molecule belonging to the immunoglobulin superfamily, featuring:

• Three extracellular immunoglobulin-like loops
• A single transmembrane domain
• A cytoplasmic region

This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus, mediating viral entry into epithelial and neuronal cells.
Mutations in this gene are associated with cleft lip and palate/ectodermal dysplasia 1 syndrome and non-syndromic cleft lip with or without cleft palate.
Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: PA5-100730_JLP_O60271-1_Rabbit.svg, PA5-100730_JLP_O60271-1_Rabbit_PDP.jpeg)