Thermo Fisher Scientific Abatacept Humanized Recombinant Human Monoclonal Antibody

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Chemical

Host/Isotype

Human / IgG1, Fc

Expression System

CHO cells

Class

Recombinant Monoclonal

Type

Antibody

Immunogen

Recombinant Human CD80 and /orCD86.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS

Contains

no preservative

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Product Specific Information

Compatible with Direct ELISA

Target Information

Abatacept, also known as Orencia, is a medication utilized for the treatment of autoimmune diseases like rheumatoid arthritis. By interfering with the immune activity of T cells, Abatacept helps in managing these conditions. It is a fusion protein that combines the extracellular domain of CTLA-4 with the Fc region of the immunoglobulin IgG1. Abatacept is a medication that is utilized as a second-line treatment for adults with moderate to severe rheumatoid arthritis (RA). For individuals whose RA is severe and rapidly progressing, it can be used as a first-line treatment. Furthermore, Abatacept is also prescribed for the treatment of psoriatic arthritis and juvenile idiopathic arthritis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.