Thermo Fisher Scientific FcRL5 Polyclonal Antibody
Thermo Fisher Scientific의 FcRL5 Polyclonal Antibody는 인간 FcRL5 단백질을 인식하는 토끼 다클론 항체로, Western blot 및 ELISA에 적합합니다. 세포막 단백질 검출에 유용하며, 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 16–190 of human FCRL5 (NP_001182317.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.94 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805575 |
Product Specific Information
Immunogen sequence:
QFARTPRPII FLQPPWTTVF QGERVTLTCK GFRFYSPQKT KWYHRYLGKE ILRETPDNIL EVQESGEYRC QAQGSPLSSP VHLDFSSASL ILQAPLSVFE GDSVVLRCRA KAEVTLNNTI YKNDNVLAFL NKRTDFHIPH ACLKDNGAYR CTGYKESCCP VSSNTVKIQV QEPFT
Positive Samples: Jurkat, PC-12, SP2/0
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
Fc receptor homologs (FcRH5), also known as IRTA2 proteins, are transmembrane proteins with sequence homology to classical Fc receptor families. FcRH5 functions as activating or inhibitory receptors on discrete B cell populations and are involved in B-cell development and differentiation in peripheral lymphoid organs. FcRH5 expression is deregulated in multiple myeloma and Burkitt lymphoma cell lines with 1q21 abnormalities. FcRH5 may play a critical role in the pathogenesis of B-cell lymphoma.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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