Thermo Fisher Scientific SynGAP Polyclonal Antibody
SynGAP 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ICC 등 다양한 응용에 사용 가능. 인간과 마우스에 반응하며, 뇌 시냅스 단백질 연구에 적합. 고순도 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ESAHIEREEYKLKEY, from the internal region near the C-terminus of SYNGAP1 (aa 1169–1183) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554518 |
Product Specific Information
This antibody is predicted to react with human, rat, dog, pig, and cow based on sequence homology.
It has been tested in Peptide ELISA with an antibody detection limit dilution of 1:32,000.
Target Information
Synaptic Ras-GTPase activating protein (SynGAP) is a PDZ-domain interacting protein expressed almost exclusively in the brain.
SynGAP is a major component of the postsynaptic density and associates with PSD-95 and NMDA receptors.
Its Ras-GTPase activity is inhibited by phosphorylation by CaM kinase II.
SynGAP is proposed to function as a negative regulator of MAP kinase activation in the absence of active NMDA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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