Thermo Fisher Scientific MBTPS1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MBTPS1. Recombinant protein control fragment (Product #RP-104051). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MBTPS1,uniProtId:Q14703-1,ncbiNodeId:9606,antigenRange:633-764,antigenLength:1052,antigenImageFileName:PA5-63247_MBTPS1_Q14703-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63247_MBTPS1_Q14703-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643795

Product Specific Information

Immunogen sequence: YPPGYFPRDN LRMKNDPLDW NGDHIHTNFR DMYQHLRSMG YFVEVLGAPF TCFDASQYGT LLMVDSEEEY FPEEIAKLRR DVDNGLSLVI FSDWYNTSVM RKVKFYDENT RQWWMPDTGG ANIPALNELL SV

Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.

Target Information

This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.