Thermo Fisher Scientific Growth Hormone Monoclonal Antibody (03)

Thermo Fisher Scientific Growth Hormone Monoclonal Antibody (Clone 03)

Applications

• ELISA (ELISA)
  Tested Dilution: 1:1,000–1:10,000

Product Specifications

Product Specific Information

Specificity: Human Growth Hormone

Target Information

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones that play an important role in growth control.
The GH1 gene, along with four additional related genes, is located at the growth hormone locus on chromosome 17. These five genes share a remarkably high degree of sequence identity, and alternative splicing results in five isoforms ranging from approximately 19 kDa to 24 kDa.

hGH is produced by somatotroph cells in the pituitary and acts through binding to membrane receptors belonging to the cytokine receptor subfamily. Its major role in stimulating body growth is mediated through stimulation of the liver and other tissues to secrete IGF-1. It promotes differentiation and proliferation of myoblasts and enhances amino acid uptake and protein synthesis in muscle and other tissues.
Mutations or deletions in the gene lead to growth hormone deficiency and short stature.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.