Thermo Fisher Scientific Cystatin 8 Polyclonal Antibody
Thermo Fisher Scientific의 Cystatin 8 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하는 고품질 항체입니다. Western blot에 최적화되어 있으며, 합성 펩타이드 면역원으로 제작되었습니다. 액상 형태로 제공되며, -20°C 보관 시 안정적입니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CST8 (Accession O60676), corresponding to amino acid residues L81–E131 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853102 |
Product Specific Information
Antibody detects endogenous levels of total CST8.
Target Information
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes.
The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for cystatin inhibition of C1 cysteine proteases. They are preferentially expressed in postmeiotic germ cells, the proximal caput epididymidis, and anterior pituitary gonadotrophs.
Therefore, CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin 8 is a 142 amino acid protein expressed in the proximal caput region of the epididymis, where it performs a specialized role during sperm development and maturation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-103769_Cystatin_8_O60676-1_Rabbit.svg)
(이미지: PA5-103769_Cystatin_8_O60676-1_Rabbit_PDP.jpeg)
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