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Thermo Fisher Scientific GPR65 Polyclonal Antibody
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Human GPR65 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용되며, 높은 종간 교차 반응성을 보입니다.
- 카탈로그번호
- PA533754
- 판매단위
- pk
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마지막 업데이트 2025. 08. 01. 오후 06:32
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Thermo Fisher Scientific PA533754 GPR65 Polyclonal Antibody 50 ug pk판매 단위 pk ·
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700,900원VAT 포함 770,990원
Thermo Fisher Scientific · Thermo Fisher Scientific GPR65 Polyclonal Antibody
Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 9–23 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR65 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551125 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey (100%)
- Gibbon, Marmoset (95%)
- Rabbit (84%)
Target Information
GPR65 (also known as TDAG8) is a transmembrane protein belonging to the G protein coupled receptor superfamily.
- Composed of 337 amino acids with 90% similarity and 81% identity in the 7 transmembrane domains of its mouse homolog.
- Contains 3 potential N-linked glycosylation sites.
- Expressed predominantly in lymphoid organs and cancer tissues, with increased expression during activation-induced death of T-cell hybridomas.
- Two major transcripts (4.5 kb and 1.8 kb) are found in peripheral blood leukocytes.
- Functions as a novel proton-sensing receptor, coupling to adenylyl cyclase and psychosine.
- Involved in immunological autotolerance and cellular transformation via RhoA activation and actin rearrangement under tissue acidosis conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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