Thermo Fisher Scientific ZMYM4 Polyclonal Antibody
ZMYM4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 IHC(Paraffin)에서 사용 가능. Human 및 Mouse 반응성. 항원 친화 크로마토그래피로 정제되었으며, 고순도(>95%)를 보장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 804–856 of Human ZMYM4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2720996 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have diverse functions such as transcriptional activation or repression. The protein folding and DNA-binding ability are governed by the coordination of a zinc ion.
ZMYM4 has been found to be overexpressed in human lung adenocarcinomas and squamous cell carcinomas. Overexpression of a fragment of the 3′UTR of the ZMYM4 mRNA, termed Cell Death Inhibiting RNA (CDIR), protects HeLa cells from IFN-γ-induced apoptosis, suggesting a potential role of ZMYM4 in tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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